Every small improvement may open up more possibilities

The first and only FDA-approved
treatment for Rett syndrome

Learn more about DAYBUE^®

Kate, age 9, living with Rett syndrome, being shown a sparkler by her mom and dad. The light makes a circle around Kate

Holly, age 11, on
DAYBUE since 2023

The only FDA-approved treatment for girls, boys, and adults living with Rett syndrome

Every day, families are seeing more of
what's possible for their
loved ones

See DAYBUE^® stories

Maddy, age 20, living with Rett syndrome, with her mom. The light makes a circle around Maddy.

Maddy, age 21, on DAYBUE
since 2020, with her mom

Can help to improve the signs and symptoms
of Rett syndrome

See study results

Clare, age 8, living with Rett syndrome, holding an ice cream cone. The light makes a circle around Clare.

Madelyn, age 5, on DAYBUE
since 2023, with her mom

Every small improvement may open up more possibilities

The first and only FDA-approved
treatment for Rett syndrome

Learn more about DAYBUE^®

Holly, age 11, on
DAYBUE since 2023

The only FDA-approved treatment for girls, boys, and adults living with Rett syndrome

Every day, families are seeing more of
what's possible for their
loved ones

See DAYBUE^® stories

Maddy, age 21, on DAYBUE
since 2020, with her mom

Can help to improve the signs and symptoms
of Rett syndrome

See study results

Madelyn, age 5, on DAYBUE
since 2023, with her mom

Every small improvement may open up more possibilities

The first and only FDA-approved
treatment for Rett syndrome

Learn more about DAYBUE^®

Holly, age 11, on
DAYBUE since 2023

The only FDA-approved treatment for girls, boys, and adults living with Rett syndrome

Every day, families are seeing more of
what's possible for their
loved ones

See DAYBUE^® stories

Maddy, age 21, on DAYBUE
since 2020, with her mom

Can help to improve the signs and symptoms
of Rett syndrome

See study results

Madelyn, age 5, on DAYBUE
since 2023, with her mom

Learn more about DAYBUE^®

DAYBUE [day-BYOO], the first and only FDA-approved treatment for Rett syndrome in adults and children ages 2 years and older.

Holly (left), Henry (top right), and Maddy  (bottom right), living with Rett syndrome

Their stories show
what may be possible

Learn more about Holly, Henry, and Maddy's experiences with DAYBUE, plus the stories of other families.

Read their stories

What is
DAYBUE?

DAYBUE is a prescription medication taken orally that treats Rett syndrome.

Learn more about DAYBUE

What to expect
with DAYBUE

Learn about the LAVENDER™ clinical study, including the benefits of DAYBUE and the most common side effects.

Learn clinical study results

Starting treatment
with DAYBUE?

Let us take you through the treatment process so you know what to anticipate.

Getting started

Support by your side

Acadia Connect is a patient and family support program that connects you and your family with educational support and resources throughout the DAYBUE treatment journey.

Call Acadia Connect at 1-844-737-2223, Monday to Friday, 8AM to 8PM ET, to learn more about our individualized support program designed to help meet the needs of your loved one taking DAYBUE.

Learn how we can help

Register for updates

Share your
DAYBUE experience

Tell us how DAYBUE has affected the signs and symptoms of Rett syndrome in your loved one.

Learn more

Follow DAYBUE on social media for more great content

Facebook

Instagram

YouTube

Important Safety Information and Indication

What are the possible side effects of DAYBUE?

Diarrhea: Diarrhea is a common side effect of DAYBUE that can sometimes be severe. Diarrhea may cause you to lose too much water from your body (dehydration). Before starting treatment with DAYBUE, stop taking laxatives. Tell your healthcare provider if you have diarrhea while taking DAYBUE. Your healthcare provider may ask you to increase the amount you drink or take antidiarrheal medicine as needed.
Vomiting: Vomiting is a common side effect of DAYBUE. Sometimes vomit can get into your lungs (aspiration), which could cause an infection (aspiration pneumonia). Tell your healthcare provider if you have severe vomiting or if vomiting happens often.
Weight loss: DAYBUE can cause weight loss. Tell your healthcare provider if you notice you are losing weight at any time during treatment with DAYBUE.
The most common side effects of DAYBUE were diarrhea and vomiting. Other side effects include fever, seizure, anxiety, decreased appetite, tiredness, and the common cold. These are not all the possible side effects of DAYBUE. Tell your healthcare provider if you have any side effects that bother you or do not go away.

What should I tell my healthcare provider before taking DAYBUE?

Before taking DAYBUE, tell your healthcare provider about all of your medical conditions, including if you:

have kidney problems.
are pregnant or plan to become pregnant. It is not known if DAYBUE will harm your unborn baby.
are breastfeeding or plan to breastfeed. It is not known if DAYBUE passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby while taking DAYBUE.

Tell your healthcare provider about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Taking DAYBUE with certain medicines may affect how the other medicines work and can cause serious side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088. You can also call Acadia Pharmaceuticals Inc. at 1-844-4ACADIA (1-844-422-2342).

What is DAYBUE?

DAYBUE is a prescription medicine used to treat Rett syndrome in adults and children 2 years of age and older. It is not known if DAYBUE is safe and effective in children under 2 years of age.

DAYBUE is available as an oral solution (200 mg/mL).

The risk information provided here is not comprehensive. To learn more, talk with your healthcare provider and read the fullPrescribing Information,Patient Information, also available at DAYBUE.com.

Important Safety Information and Indication

What are the possible side effects of DAYBUE?

Diarrhea: Diarrhea is a common side effect of DAYBUE that can sometimes be severe. Diarrhea may cause you to lose too much water from your body (dehydration). Before starting treatment with DAYBUE, stop taking laxatives. Tell your healthcare provider if you have diarrhea while taking DAYBUE. Your healthcare provider may ask you to increase the amount you drink or take antidiarrheal medicine as needed.
Vomiting: Vomiting is a common side effect of DAYBUE. Sometimes vomit can get into your lungs (aspiration), which could cause an infection (aspiration pneumonia). Tell your healthcare provider if you have severe vomiting or if vomiting happens often.
Weight loss: DAYBUE can cause weight loss. Tell your healthcare provider if you notice you are losing weight at any time during treatment with DAYBUE.
The most common side effects of DAYBUE were diarrhea and vomiting. Other side effects include fever, seizure, anxiety, decreased appetite, tiredness, and the common cold. These are not all the possible side effects of DAYBUE. Tell your healthcare provider if you have any side effects that bother you or do not go away.

What should I tell my healthcare provider before taking DAYBUE?

Before taking DAYBUE, tell your healthcare provider about all of your medical conditions, including if you:

have kidney problems.
are pregnant or plan to become pregnant. It is not known if DAYBUE will harm your unborn baby.
are breastfeeding or plan to breastfeed. It is not known if DAYBUE passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby while taking DAYBUE.

What is DAYBUE?

DAYBUE is a prescription medicine used to treat Rett syndrome in adults and children 2 years of age and older. It is not known if DAYBUE is safe and effective in children under 2 years of age.

DAYBUE is available as an oral solution (200 mg/mL).

The risk information provided here is not comprehensive. To learn more, talk with your healthcare provider and read the full Prescribing Information, including Patient Information, also available at DAYBUE.com.

Every small improvement may open up more possibilities

The only FDA-approved treatment for girls, boys, and adults living with Rett syndrome

Can help to improve the signs and symptoms of Rett syndrome

Every small improvement may open up more possibilities

The only FDA-approved treatment for girls, boys, and adults living with Rett syndrome

Can help to improve the signs and symptoms of Rett syndrome

Every small improvement may open up more possibilities

The only FDA-approved treatment for girls, boys, and adults living with Rett syndrome

Can help to improve the signs and symptoms of Rett syndrome

DAYBUE [day-BYOO], the first and only FDA-approved treatment for Rett syndrome in adults and children ages 2 years and older.

Their stories show what may be possible

What isDAYBUE?

What to expectwith DAYBUE

Starting treatmentwith DAYBUE?

Support by your side

Register for updates

Share your DAYBUE experience

Follow DAYBUE on social media for more great content

Important Safety Information and Indication

What are the possible side effects of DAYBUE?

What should I tell my healthcare provider before taking DAYBUE?

What is DAYBUE?

Important Safety Information and Indication

What are the possible side effects of DAYBUE?

What should I tell my healthcare provider before taking DAYBUE?

What is DAYBUE?

WE'RE MIXING IT UP!

You're about to leave DAYBUE.com

A Letter to the Rett Syndrome Community: Updates From Acadia

Can help to improve the signs and symptoms
of Rett syndrome

Can help to improve the signs and symptoms
of Rett syndrome

Can help to improve the signs and symptoms
of Rett syndrome

Their stories show
what may be possible

What is
DAYBUE?

What to expect
with DAYBUE

Starting treatment
with DAYBUE?

Share your
DAYBUE experience