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Quinn

Quinn is a social girl who loves to make friends and lights up when she sees the school bus

Quinn’s family has seen meaningful improvements in the signs and symptoms of Rett syndrome since starting DAYBUE^®.

For Quinn, some improvements include:

Quinn, age 6, living with Rett syndrome

Hand movements or stereotypies

Quinn has more control of her hands and she grabs at her face and body less

Repetitive behaviors

Quinn’s teeth grinding has improved

Breathing

Quinn still holds her breath occasionally, has fewer “Rett episodes,” and hyperventilates less

Eye gaze

Quinn can hold her gaze to participate and engage, especially in the classroom and in her therapies

Mood

Quinn’s moods are more predictable and she cries a lot less

Quinn’s story

Diagnosis and symptoms

Quinn was diagnosed with Rett syndrome when she was 15 months old. Some of her signs and symptoms have included:

Breath holding
Repetitive behaviors (teeth grinding)
Loss of purposeful hand use

Other treatments

At school, Quinn participates in physical, speech, and occupational therapy. Outside of school, Quinn does additional physical, oral motor, and swim therapy.

Managing side effects

After starting DAYBUE, Quinn began experiencing diarrhea. Some days, it occurs once or twice, other days as much as seven times. Quinn’s parents worked with their doctor on different tactics to help manage the diarrhea.

Important Note: The effectiveness and safety of DAYBUE were evaluated in the 12-week LAVENDER™ clinical study of 187 female patients aged 5 to 20 with Rett syndrome. Because each individual with Rett syndrome is unique—with a unique set of symptoms—the response to DAYBUE may be different for everyone. Quinn was a DAYBUE clinical study participant and continued to take DAYBUE. Quinn’s experience on treatment is unique to her. See the results from the clinical study. Quinn’s family was compensated for sharing their story and participating in a photo shoot. This story was created in March 2024.

The improvements in Quinn’s symptoms, especially in her mood, have given us more confidence to have more flexibility as a family. Before DAYBUE, we didn’t go to many places. Now we can all go to parties, family cookouts, and our other kids’ sports events.

— Lindsay, Quinn’s mom

Important Safety Information and Indication

What are the possible side effects of DAYBUE?

Diarrhea: Diarrhea is a common side effect of DAYBUE that can sometimes be severe. Diarrhea may cause you to lose too much water from your body (dehydration). Before starting treatment with DAYBUE, stop taking laxatives. Tell your healthcare provider if you have diarrhea while taking DAYBUE. Your healthcare provider may ask you to increase the amount you drink or take antidiarrheal medicine as needed.
Vomiting: Vomiting is a common side effect of DAYBUE. Sometimes vomit can get into your lungs (aspiration), which could cause an infection (aspiration pneumonia). Tell your healthcare provider if you have severe vomiting or if vomiting happens often.
Weight loss: DAYBUE can cause weight loss. Tell your healthcare provider if you notice you are losing weight at any time during treatment with DAYBUE.
The most common side effects of DAYBUE were diarrhea and vomiting. Other side effects include fever, seizure, anxiety, decreased appetite, tiredness, and the common cold. These are not all the possible side effects of DAYBUE. Tell your healthcare provider if you have any side effects that bother you or do not go away.

What should I tell my healthcare provider before taking DAYBUE?

Before taking DAYBUE, tell your healthcare provider about all of your medical conditions, including if you:

have kidney problems.
are pregnant or plan to become pregnant. It is not known if DAYBUE will harm your unborn baby.
are breastfeeding or plan to breastfeed. It is not known if DAYBUE passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby while taking DAYBUE.

Tell your healthcare provider about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Taking DAYBUE with certain medicines may affect how the other medicines work and can cause serious side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088. You can also call Acadia Pharmaceuticals Inc. at 1-844-4ACADIA (1-844-422-2342).

What is DAYBUE?

DAYBUE is a prescription medicine used to treat Rett syndrome in adults and children 2 years of age and older. It is not known if DAYBUE is safe and effective in children under 2 years of age.

DAYBUE is available as an oral solution (200 mg/mL).

The risk information provided here is not comprehensive. To learn more, talk with your healthcare provider and read the fullPrescribing Information,Patient Information, also available at DAYBUE.com.

Important Safety Information and Indication

What are the possible side effects of DAYBUE?

Diarrhea: Diarrhea is a common side effect of DAYBUE that can sometimes be severe. Diarrhea may cause you to lose too much water from your body (dehydration). Before starting treatment with DAYBUE, stop taking laxatives. Tell your healthcare provider if you have diarrhea while taking DAYBUE. Your healthcare provider may ask you to increase the amount you drink or take antidiarrheal medicine as needed.
Vomiting: Vomiting is a common side effect of DAYBUE. Sometimes vomit can get into your lungs (aspiration), which could cause an infection (aspiration pneumonia). Tell your healthcare provider if you have severe vomiting or if vomiting happens often.
Weight loss: DAYBUE can cause weight loss. Tell your healthcare provider if you notice you are losing weight at any time during treatment with DAYBUE.
The most common side effects of DAYBUE were diarrhea and vomiting. Other side effects include fever, seizure, anxiety, decreased appetite, tiredness, and the common cold. These are not all the possible side effects of DAYBUE. Tell your healthcare provider if you have any side effects that bother you or do not go away.

What should I tell my healthcare provider before taking DAYBUE?

Before taking DAYBUE, tell your healthcare provider about all of your medical conditions, including if you:

have kidney problems.
are pregnant or plan to become pregnant. It is not known if DAYBUE will harm your unborn baby.
are breastfeeding or plan to breastfeed. It is not known if DAYBUE passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby while taking DAYBUE.

What is DAYBUE?

DAYBUE is a prescription medicine used to treat Rett syndrome in adults and children 2 years of age and older. It is not known if DAYBUE is safe and effective in children under 2 years of age.

DAYBUE is available as an oral solution (200 mg/mL).

The risk information provided here is not comprehensive. To learn more, talk with your healthcare provider and read the full Prescribing Information, including Patient Information, also available at DAYBUE.com.

Meet Quinn

Quinn is a social girl who loves to make friends and lights up when she sees the school bus

Quinn’s story

The improvements in Quinn’s symptoms, especially in her mood, have given us more confidence to have more flexibility as a family. Before DAYBUE, we didn’t go to many places. Now we can all go to parties, family cookouts, and our other kids’ sports events.

Important Safety Information and Indication

What are the possible side effects of DAYBUE?

What should I tell my healthcare provider before taking DAYBUE?

What is DAYBUE?

Important Safety Information and Indication

What are the possible side effects of DAYBUE?

What should I tell my healthcare provider before taking DAYBUE?

What is DAYBUE?

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A Letter to the Rett Syndrome Community: Updates From Acadia